Pruning to increase yield: how to prune cannabis, and what the research found

3.5 to 4 weeks

into flower, when USask suggests clearing lower growth

10th node

where a 2022 indoor study topped its plants

8

plant-shaping treatments compared in a 2021 greenhouse study

Pruning to increase yield works, within limits. In a 2022 indoor study, topped plants produced more dried flower than unpruned ones, but their total CBD yield was not significantly different. A 2021 greenhouse study found that clearing leaves and lower branches mostly evened out cannabinoid levels through the plant, while one repeated pruning schedule raised flower yield. For a home grower the lesson is to prune with a purpose: take off what gets no light, keep the leaves that feed the buds, and time the cuts around the stretch.

This is the pruning guide in our growing series. For the choice between bending and cutting the main stem, see LST versus topping; for the vocabulary, the grower’s glossary; and for the whole grow, our home-grow guide.

Last reviewed: November 2026.

Pruning to increase yield: what two studies found

Massuela and colleagues (2022) grew one CBD-dominant medical cannabis genotype indoors and compared three treatments: topping at the tenth node, a lollipop treatment that removed the lowest side branches, and an unpruned control. Pruning happened 27 days after planting. Topped plants produced significantly more dried flower and leaf than the other two, and pushed more of their flower toward the top of the plant. Total CBD yield showed a trend of topped above control above lollipop, but neither pruned group differed significantly from the control.

What each cut did in the studies

Pick a treatment to see the measured result.

More flower

Topping

Massuela 2022: more dried flower and leaf than unpruned plants; total CBD yield not significantly different.

Lowest CBD yield

Lollipop

Massuela 2022: removing the lowest side branches gave taller plants with fewer side shoots and the lowest CBD yield, though not significantly below the control.

More flower

Double prune

Danziger and Bernstein 2021: a second cut at the switch to flowering gave shorter, bushier plants and higher flower yield than the control.

More even

Defoliation

Danziger and Bernstein 2021: more light reached the lower canopy and cannabinoid levels there rose; flower yield did not change significantly.

Danziger and Bernstein (2021) tested eight shaping treatments on Topaz, a high-CBD cultivar grown to about 2.5 meters in a greenhouse. Defoliation and removing bottom branches and leaves let more light into the lower canopy and raised cannabinoid concentrations there, making the plant more uniform. Flower yield moved for only two treatments: a double prune, with a second cut at the switch to flowering, gave more, and stripping the primary branches gave less.

Both studies used CBD-type plants in research settings, and a home tent will behave differently. Their findings still line up with what the university grow guides advise.

How to prune marijuana plants during vegetative growth

Step 1: remove dead or damaged leaves as soon as you see them. The University of Saskatchewan grow guide says that applies whatever your pruning style.

Step 2: do any shaping cuts, such as topping or pinching growth tips, during vegetative growth. USask’s vegetative guide describes training as optional and done to control size and shape. Our LST versus topping guide covers how to choose.

Where the cuts go

Three cuts and one thing to leave alone

1234
  1. 1

    Dead or damaged leaves

    Any time, whatever your pruning style

    They no longer feed the plant.

    University of Saskatchewan grow guide
  2. 2

    The main tip (topping)

    During vegetative growth. Massuela 2022 topped at the tenth node, 27 days after planting

    Topped plants gave significantly more dried flower in that study.

    Massuela and colleagues, 2022
  3. 3

    Low branches and shaded leaves

    At the early-to-late flower transition, about 3.5 to 4 weeks after the switch to 12 hours of light

    They rarely make good flower, and clearing them helps airflow.

    University of Saskatchewan grow guide
  4. 4

    Healthy fan leaves: keep them

    Through flowering

    Leaves photosynthesize and store nutrients the plant draws on later.

    University of Saskatchewan grow guide

Between plants: clean the blade with a bleach solution. Ethanol and hydrogen peroxide do not inactivate hop latent viroid.OSU Extension

Illustration, not to scale. Both studies used CBD-type plants in research settings; a home tent will behave differently.

Step 3: clean the blade between plants. OSU Extension says hop latent viroid moves on tools through plant sap, and that bleach solutions inactivate it where ethanol and hydrogen peroxide do not.

If fan leaves turn yellow during veg, look at feeding and watering before you reach for the snips. USask notes that nitrogen is usually the limiting nutrient in vegetative growth and that overwatering damages roots. Cutting yellow leaves treats the sign, and the cause stays.

Trimming during the flower stage: lollipopping and fan leaves

Hold off early. USask advises against pruning branches in early flower because it can cause stretching beyond what the plant would do anyway. Its recommended window is the transition from early to late flower, about 3.5 to 4 weeks after you switch to 12 hours of light for most varieties.

Scroll the timeline

When to prune, from veg to harvest

Timing from the University of Saskatchewan grow guides.

Vegetative growth

Shape here

Topping, pinching and bending all belong in veg, while the plant grows fastest.

Flip to 12/12

Stop cutting branches

Pruning in early flower can add to the stretch.

Weeks 3.5 to 4

Clear the understory

Remove shaded lower leaves, leaves covering bud sites and small lower branches.

Late flower

Keep the canopy

Leave healthy fan leaves; they feed the plant to the end.

Harvest

Trim wet or dry

Remove fan leaves and manicure sugar leaves before or after drying.

Remove dead or damaged leaves at any stage.

At that point, take the lower leaves that get no light, especially ones covering bud sites, and the small lower branches. USask says those branches rarely produce good flower under the canopy, and clearing them improves airflow and cuts harvest work. That is lollipopping in all but name.

Can you remove all the fan leaves during flowering? You can, but the USask author does the opposite and leaves as many as possible, because leaves photosynthesize and store nutrients the plant can draw on later. As long as the canopy is full and using the light, the plant is in good shape.

Outdoor plants need even less. USask says flower-stage leaf pruning is generally unnecessary outside, because the sun reaches every part of the plant. Dead or damaged leaves still come off.

CutWhenWhat it does
Dead or damaged leavesAny time (USask)Removes tissue that no longer feeds the plant
ToppingVegetative growth (USask); tenth node at 27 days after planting in Massuela 2022Shorter plant, more side shoots; more dried flower in Massuela 2022
Lower branches (lollipopping)About 3.5 to 4 weeks into flower (USask)Clears branches that rarely make good flower under the canopy
Selective defoliationAbout 3.5 to 4 weeks into flower (USask)Light and airflow to bud sites; more even cannabinoids in Danziger and Bernstein 2021

The last cut: harvest trimming

The final round of pruning happens at harvest. The USask harvesting guide describes wet trimming, where you cut branches, strip fan leaves and manicure sugar leaves right away, and dry trimming, where you hang the plant whole and trim after it dries. Wet trimming speeds drying; dry trimming is handy when you need to harvest but cannot spend hours trimming that day.

Either way, save the trim if you like: USask notes that some growers collect the resinous sugar leaves for hash or edibles. Keep the plant count in mind as you plan the next round, too: Health and Safety Code section 11362.2(a)(3) allows not more than six living plants per private residence in California, however many adults live there. This is general information, not legal advice.

Frequently asked questions

How do you prune marijuana plants?

Remove dead or damaged leaves whenever you see them, do topping or tip pinching during vegetative growth, and wait until about 3.5 to 4 weeks into flower to clear shaded lower leaves and small lower branches. Clean the blade between plants.

Can you remove all fan leaves during flowering?

It is possible, but University of Saskatchewan guidance favors keeping healthy fan leaves, because they photosynthesize and store nutrients. Remove shaded lower leaves and leaves covering bud sites around 3.5 to 4 weeks into flower, plus any dead or damaged leaves.

When should you lollipop your plants?

USask suggests clearing lower branches and leaves at the transition from early to late flower, about 3.5 to 4 weeks after switching to 12 hours of light, and avoiding branch pruning in early flower because it can add to the stretch.

When should you trim fan leaves on pot plants?

Trim dead or damaged fan leaves at any stage. Healthy fan leaves can come off selectively around 3.5 to 4 weeks into flower when they shade bud sites, and the rest come off at harvest, before or after drying.

Sources

For adults 21+ (18+ with a physician’s recommendation in California). Keep out of reach of children and pets. Do not drive or operate machinery after use.

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